All are welcome, (attendance required for graduate students). Lunch is provided.

Michael Miller, Department of Biomedical Engineering, Johns Hopkins University

Computational anatomy and diffeomorphometry: Embedding the brain at meso-scale into the soft-tissue condensed matter continuum.

I will discuss diffeomorphometry, the major tool of Compuational anatomy (CA) for placing human shape and form into metric spaces via diffeomorphic correspondences. I will connect the variational approaches of CA to the Euler-Lagrange equations which provide a dynamical systems model on the continuum grouped in terms of forces - velocities - accelerations that we use to represent processes manifesting either atrophy or growth. I will discuss applications via examples of circuits measured via magnetic resonance imaging being examined in our studies of neurodegenerative illness.