Tal Danino

Assistant Professor of Biomedical Engineering

1000M Northwest Corner Building
550 W 120th St
New York, NY 10027

Phone: +1 212-853-0787
Fax: +1 212-854-8725
Email: td2506@columbia.edu

Research Areas:
Synthetic biology. Engineering gene circuits in microbes. Cancer therapeutics and diagnostics. Mathematical modeling of gene network dynamics. Microfluidics. Biosensor applications.    
 

Education

2015, Postdoctoral Fellow, Massachusetts Institute of Technology
2011, Ph.D.  Bioengineering, University of California, San Diego
2005, B.S.  Physics, Chemistry, Math, University of California, Los Angeles

Professional Experience

2016-present : Assistant Professor, Biomedical Engineering, Columbia University, New York, NY

Publications

Din, O., Danino, T., Prindle, A., Skalak, M., Selimkhanov, J., Allen, K., Julio, E., Atolia, A., Tsimring, L., Bhatia, S., Hasty, J.  Synchronized cycles of bacterial lysis for in vivo delivery.  Nature doi:10.1038/nature18930 (2016)

Luna, J., Scheel, T., Danino, T., Shaw, K., Takacs, C., Mele, A., Fak, J., Nishiuchi, E., Cantanese, M., Rice, C., Darnell, R.  Hepatitis C virus RNA functionally sequesters miR-122.  Cell  160(6), 1099–1110 (2015)

Danino, T.*, Prindle, A.*, Kwong, G., Skalak, M., Li, H., Allen, K., Hasty, J., and Bhatia, S.  Programmable Probiotics: Gene Circuit Chaperones for Non-invasive Cancer DetectionSci. Transl. Med. 7, 289ra84 (2015) 

Danino, T.*, Prindle, A.*, Hasty, J., and Bhatia, S.  Measuring growth and gene expression dynamics of tumor-targeted S. typhimurium bacteria. Journal of Visualized Experiments 77, e50540 (2013)

Prindle, A., Selimkhanov, J.S.,  Danino, T., Samayoa, P., Goldberg, A., Bhatia, S., and Hasty, J.  Synthetic biology in clinically relevant microbes. ACS Synthetic biology 1(10), 458-464 (2012)

Danino, T., Lo, J., Prindle, A., Hasty, J., and Bhatia, S.  In vivo gene expression dynamics from tumor-targeted bacteria. ACS Synthetic biology 1(10), 465-470 (2012)

Cookson, N.A.*, Mather, W.H.*, Danino, T., Mondragón-Palomino, O., Williams, R. J., Tsimring, L. S., and Hasty, J.  Queueing up for enzymatic processing: Correlated signaling through coupled degradation. Molecular Systems Biology 7:561, (2011)

Prindle, A.*, Samayoa, P.*, Razinkov, I., Danino, T., Tsimring, L.S. and Hasty, J.  Sensing array of radically coupled genetic biopixels. Nature 481, 39-44 (2011)

Mondragon-Palomino, O., Danino, T., Selimkhanov, J., Tsimring, L.S., and Hasty, J.  Entrainment of a population of synthetic genetic oscillators. Science 333(6047), 1315-1319 (2011)

Boyer, D., Mather, W., Mondragon-Palomino, O., Orozco-Fuentes, S., Danino, T., Hasty, J., and Tsimring, L. S.  Buckling instability in ordered bacterial colonies. Physical Biology 8, 026008 (2011)

Danino,T., Volfson, D., Bhatia, S., Tsimring, L., and Hasty, J.  In-silico pattern formation of vascular mesenchymal stem-cells in three-dimensions. PLoS ONE 6(5), e20182 (2011)

Mather, W., Mondragon-Palomino, O., Danino, T., Hasty, J., and Tsimring, L.S.  Streaming instability in growing cell populations. 
Physical Review Letters 104(20), 208101 (2010)

Danino, T.*, Mondragon-Palomino, O.*, Tsimring, L., and Hasty, J.  A synchronized quorum of genetic clocks. Nature 463, 326-330 (2010)

 

 

 

 

 

 

 

 


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