Samuel K. Sia

Associate Professor of Biomedical Engineering

351 Engineering Terrace
1210 Amsterdam Avenue, Mail Code: 8904
New York , NY 10027

Phone: +1 212-854-7549
Fax: +1 212-854-8725

Research Areas:

Microfluidics, point-of-care diagnostics, 3D tissue engineering, implantable devices.
Lab Web Site


  • 1997: B.S. Biochemistry, University of Alberta
  • 2002: Ph.D. Biophysics, Harvard University
  • 2002-5: Postdoctoral Fellow, Chemistry and Chemical Biology, Harvard University


Professional Experience

  • 2005-2011: Assistant Professor of Biomedical Engineering, Columbia University
  • 2011-present: Associate Professor of Biomedical Engineering, Columbia University



  • BMEN 4210 (Fall) - Thermodyanmics of Biological Systems
  • BMEN 4590 (Spring) - BioMEMS: Cellular and Molecular Applications


Honors and Awards

  • 1993-97: Canada Scholar
  • 1997: Dean's Silver Medal in Science, University of Alberta
  • 1997-99: National Science and Engineering Council of Canada Postgraduate Scholarship A
  • 1999-2001: National Science and Engineering Research Council of Canada Postgraduate Scholarship B
  • 1997-2002: Howard Hughes Medical Institute Predoctoral Fellowship
  • 2002: Delegate, International Achievement Summit, Dublin, Ireland
  • 2002: Harvard University Certificate of Distinction in Teaching
  • 2004-5: Canadian Institutes of Health Research Fellowship
  • 2006 American Heart Association Scientist Development Grant
  • 2006 Walter H. Coulter Early Career Award
  • 2007 National Academy of Engineering Frontiers Symposium
  • 2008 NSF CAREER Award
  • 2008 Walter H. Coulter Early Career Award, Phase II
  • 2010 NASA Launch innovator
  • 2010 MIT Technology Review 35


selected Publications

  • S.K. Sia and C.D. Chin, “Sweet solution to sensing”, Nature Chemistry, 3, 659–660 (2011).

  • C.D. Chin, T. Laksanasopin, Y.K. Cheung, D. Steinmiller, V. Linder, H. Parsa, J. Wang, H. Moore, R. Rouse, G. Umviligihozo, E. Karita, L. Mwamarangwe, S. Braunstein, J. van de Wijgert, R. Sahabo, J. Justman, Wafaa El-Sadr, S.K. Sia, “Microfluidics-based diagnostics of infectious diseases in the developing world”, Nature Medicine, 17, 1015–1019 (2011).

  • H. Parsa, R. Upadhyay, and S.K. Sia, “Uncovering the behaviors of individual cells within a multicellular microvascular community”, Proc. Natl. Acad. Sci., 108, 5133-5138 (2011).

  • B.W. Lee, R. Schubert, Y.K. Cheung, F. Zannier, Q. Wei, D. Sacchi, and S.K. Sia, “Strongly Binding Cell-Adhesion Polypeptides of Programmable Valencies”, Angew. Chem. Int. Ed., 49, 1971 –1975 (2010).

  • Y.K. Cheung, E.U. Azeloglu, D.A. Shiovitz, K.D. Costa, D. Seliktar and S.K. Sia, “Microscale control of stiffness in cell-adhesive substrate using microfluidics-based lithography”, Angew. Chemie. Int. Ed., 48: 7188-7192 (2009).

  • B. M. Gillette, J. A. Jensen, B. Tang, G. J. Yang, A. Bazargan-Lari, M. Zhong and S. K. Sia, "In situ collagen assembly for integrating microfabricated three-dimensional cell-seeded matrices", 7, 636 - 640, Nature Materials. (2008). 

  • N. Damean, S.K. Sia, V. Linder, M. Navrolyansky and G.M. Whitesides, "Space- and time-resolved spectrophotometry at the microscale," Proc. Natl. Acad. Sci., 102:10035-9 (2005).

  • S.K. Sia, V. Linder, B.A. Parviz, A. Siegel and G.M. Whitesides, "Aportable and low-cost immunoassay for resource-poor settings," Angew. Chemie. Int. Ed., 43:498-502 (2004). 

  • S.K. Sia and P.S. Kim, "Protein grafting of an HIV-1 inhibiting epitope," Proc. Natl. Acad. Sci. USA, 100:9756-9761 (2003).

  • S.K. Sia, P.A. Carr, A.G. Cochran and P.S. Kim, "Mechanism of short,constrained a-helical peptides that inhibit HIV-1 entry," Proc. Natl. Acad. Sci. USA, 99:14664-14669 (2002).

Microfluidics, point-of-care diagnostics, 3D tissue engineering, implantable devices.

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