Research

The Columbia University Department of Biomedical Engineering is currently home to 19 full-time faculty, in addition to three adjunct faculty and numerous affiliates and collaborators. As a result, our Department hosts an exceptional range of cutting-edge and world-class research laboratories housed in over 50,000 square feet of space in the Morningside Heights and Health Sciences campuses. Mirroring our undergraduate and graduate curriculum, our research areas are generally associated with three research tracks: biomechanics, cell and tissue engineering, and biomedical imaging. However, it is in the overlap between these broad and diverse areas that our true strength lies.

Cell and tissue engineering includes the study of cellular mechanics and cell signaling, mechanotransduction, biosystems engineering and computational biology, nanotechnology, microfluidics, bioMEMS and gene chips, functional tissue engineering and biomaterials, tissue structure-function and cell-matrix interactions. See here for individual labs.

Biosignals and Biomedical imaging encompasses biophysics of image formation from molecules to tissues, signal detection and formation, image and signal processing using quantitative analysis, modeling the physical and biological processes, and performance evaluation. Specialty areas include MRI, ultrasound, biophotonics, microscopy, EEG, and medical imaging processing. See here for individual labs.

Biomechanics includes the topics of musculoskeletal mechanics, cardiac mechanics, mechano-electrochemical responses of soft and hard tissues, cell-matrix interactions, cellular biomechanics, functional tissue engineering, image-based functional anatomy, and computer-assisted surgery and surgical planning. See here for individual labs.


Where these fields intersect, we have established particular expertise and resources dedicated to a growing number of research fields including:

Cardiac research: Cardiac biomechanics, cardiac tissue engineering and state-of-the-art in vivo cardiac imaging.
Neuroengineering: Computational modeling of neural systems, in vivo clinical and pre-clinical neuroimaging, neurotrauma and repair research, neuronal tissue engineering.
Stem cell research:
Functional tissue engineering and regenerative medicine research using stem cells.

Microscale engineering and nanotechnology:
Cell positioning and molecular design, MEMs and lab-on-a-chip diagnostic devices, micro- and nano-fabrication techniques combined with advanced microscopy.
Orthopedics research: Musculoskeletal biomechanics, cellular and molecular bone biomechanics, bone and tissue interface tissue engineering, in vivo imaging of osteoarthritis. Our Department also has strong associations with many of Columbia University’s other leading departments and research institutions:

Radiology: The majority of our Biomedical Imaging faculty hold joint appointments in The Columbia University Medical Center Department of Radiology, contributing to the development of cutting-edge, in vivo imaging modalities.

College of Dental Medicine: Several of our cellular and tissue engineering faculty hold joint appointments in Columbia University Medical Center College of Dental Medicine. Their work focuses on stem cell based regenerative medicine and biomaterials and interface for orthopedic and dental applications.

Mechanical engineering: Our biomechanics faculty have close ties to the Columbia University Department of Mechanical Engineering.

Neurobiology and Behavior: Our imaging and cell and tissue faculty closely interact with the world-renowned Columbia Presbyterian Center for Neurobiology and Behavior.

Our many established biomedical collaborations also include: The Herbert Irving Comprehensive Cancer Center, Dermatology , Orthopedic Surgery, Sergievsky Center , Department of Neurology, Department of Biological Psychiatry, Department of Pediatrics-Oncology, Dept. Medicine-Digestive and Liver Diseases, Medicine-Cardiology, Department of Ophthalmology , Department of physiology and cellular biophysics, and the Department of Biomedical Informatics.


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