Orthopaedic Implants and Infection: Surfaces, synovial fluid, and the joint environment

Noreen J. Hickok, Ph.D.
Associate Professor
Department of Orthopaedic Surgery
Department of Biochemistry & Molecular Biology
Vice-chair, Chung Committee (Board 152), IRB
Thomas Jefferson University
Noreen J Hickok, Ph.D. is an associate professor in the Department of Orthopaedic Surgery at Thomas Jefferson University in Philadelphia, PA.  For the last 15 years, she and her colleagues within the Department and the Rothman Institute have been exploring means of preventing establishment of infection in the presence of an implant. Dr. Hickok’s research interests reflect her early training and center at the interface of nanotechnology, chemistry and biology with a strong eye towards their translation to the real world. She received her early training in chemistry, earning an S.B. from MIT and a Ph.D. from Brandeis University. Her postdoctoral research encompassed protein biochemistry, molecular endocrinology, and molecular biology first at Memorial Sloan-Kettering Cancer Center then at The Population Council in New York City. Since joining Thomas Jefferson University, her interest in cellular/bacterial interactions with surfaces and their regulation has dominated her research. This research has resulted in the development of surfaces that are antibacterial while maintaining cellular compatibility as well as new insights on the role of the implant environment 

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