Andrew Laine

Professor of Biomedical Engineering

Chair, Department of Biomedical Engineering

351 Engineering Terrace
1210 Amsterdam Avenue, Mail Code: 8904
New York, NY 10027

Phone: +1 212 854 6539
Fax: +1 212-854-8725
Email: laine@columbia.edu

Research Areas:
 
Mathematical analysis and quantification of medical images, signal and image processing, computer-aided diagnosis.

PROJECTS

  • Adaptive Spatial-Temporal Filtering Applied to X-Ray Fluoroscope
  • Micro Array Genomic Image Recognition with Multi-scale techniques
  • Fast Interpolation Algorithms for Three-Dimensional Real-Time Cardiac Ultrasound
  • Segmentation of cardiac US using level sets on alternate grids
  • Mathematical analysis and quantification of medical images, signal and image processing, computer-aided diagnosis.

 

ACADEMIC TRAINING

Colleges and Universities Attended

Cornell University, Ithaca, NY.
Bachelor of Science in Biological Science, May 1977.

University of Connecticut, Storrs, CT.
Master of Science in Chemistry, May 1980.

Washington University, St. Louis, MO.
School of Engineering and Applied Science
Master of Science in Computer Science, May 1983.

Washington University, St. Louis, MO.
School of Engineering and Applied Science
Doctor of Science in Computer Science, May 1989.

Dissertation Title:  "High-Speed Feature Based Stereo Matching."
Published:IEEE Transactions on Robotics and Automation, 1991.
Sponsor:Defense Mapping Agency, Department of Defense (DoD).
Advisor: Gruia-Catalin Roman, Ph.D., Professor and Chair

 

TRAINEESHIP

Research Appointments

1980-1983
Graduate Research Assistant - Biomedical Computing Laboratory, Department of Computer Science, Washington University, St. Louis, MO. Supported by National Institutes of Health, Project Title: "ADS: A Medical Information System SupportingAbstract Datatypes."

1983-1985
Lecturer/Research Associate - Defense Mapping Agency Professional, Development  Program in Computer Science for Image Processing, Department of Computer Science, Washington University, St. Louis, MO.

1985-1989
Research Associate - Computer Vision Group, Department of Computer Science, Washington University, St. Louis, MO.
Sponsor: Defense Mapping Agency contract DMA800-85-C-0010 (1985-1987).

1989-1990
Postdoctoral Fellow - Center for Intelligent Computer Systems, Department of Computer Science, Washington University, St. Louis, MO.

 

PROFESSIONAL ORGANIZATIONS AND SOCIETIES

Member, Technical Committee on Graphics Recognition (TC-10): International Association for Pattern Recognition (IAPR).
Member, Technical Committee, IEEE Pattern Analysis and Machine Intelligence (PAMI).
Member, Institute of Electrical and Electronics Engineers (IEEE).
Member, IEEE Computer Society.
Member, Association for Computing Machinery (ACM).
Member, Radiological Society of North America (RSNA).
Chair, Technical Committee on Medical Imaging (IEEE EMBS), 2007-2010.
ADCOM, IEEE Engineering in Medicine and Biology Society, 2007-2009 (elected officer)
Member, IEEE Engineering in Medicine and Biology Society (IEEE EMBS).
Member, IEEE Biomedical Imaging and Signal Processing, (BISP) Technical Committee
Vice President of Publications, IEEE EMBS (Executive Officer, 2008 - 2012, elected 2 terms).
IEEE Transactions on Biomedical Engineering, Editorial Board, appointed in 2012.
Journal of Visual Communication and Image Representation, Editorial Board, Appointed in 2008, Elsevier.
Chair, Steering Committee for IEEE International Symposium on Biomedical Imaging (ISBI), Serving a 2 year term, 5/2011 – 5/2013.
Conference Editorial Board, IEEE EMBS, Engineering in Biology and Medicine Annual Conference, Area Editor in Medical Imaging    and Image Processing, Appointed 2010 – present.

 

ACADEMIC APOINTMENTS

1990-1995            
Assistant Professor
Computer and Information Sciences and Engineering Department,
Center for Computer Vision and Visualization,
Universityof Florida, Gainesville, FL.

1995-1997            
Associate Professor (Promoted with tenure in July, 1995)
Department of Computer and Information Sciences and Engineering,
Department of Electrical and Computer Engineering, and
Department of Radiology,
University of Florida, Gainesville, FL.

1997-2004    
Associate Professor of Biomedical Engineering and Radiology (Physics)
Columbia University (Tenure granted, April 2000)

2002-2010            
Vice Chair, Department of Biomedical Engineering (Appointed July, 2002)
Director of Academic Programs
Columbia University, New York, NY.

2004-2010           
Professor of Biomedical Engineering and Radiology (Physics)
Vice Chair, Department of Biomedical Engineering
Columbia University, New York, NY

2011-Present        
Percy K. and Vida L. W. Hudson Professor of Biomedical Engineering
Professor, Department of Radiology
Columbia University, New York, NY

2012-Present       
Chair, Department of Biomedical Engineering
Percy K. and Vida L. W. Hudson Professor of Biomedical Engineering
Professor, Department of Radiology
Columbia University, New York, NY

 

HONORS AND AWARDS
 

Engineering Research Award, Engineering Foundation and the Institute of Electrical and Electronics Engineers (IEEE), 1991.

Research Initiation Award, National Science Foundation (NSF), 1991.

Whitaker Foundation Award in Biomedical Engineering, Whitaker Foundation, 1992.

Humboldt Research Award, Alexander von Humboldt Foundation, Bonn, Germany.
Sponsoring Institutes: Technische Universitat Darmstadt, Darmstadt, Germany, 1998        
andUniversity of Bremen, MeVis Institute, Bremen, Germany,1999.

Distinguished Alumni Award, Department of Computer Science,
School of Engineering and Applied Science, Washington University (St. Louis), January 2002.

AIMBE Fellow - American Institute for Medical and Biological Engineering (Class of 2006)

Senior Member, IEEE (2007)

IBM Faculty Award, T.J. Watson Research Center (2008, 2009)

Fellow IEEE, elevated in 2010


ACTIVE GRANTS

Agency: National Institutes of Health (NHLBI) R01 HL086578-01A2
Title: “Clinical validation of cardiac strain measures with real-time 4D ultrasound”
Role: PI, 25% effort
Period: 9/1/08 – 05/31/14 (zero-cost extension)
Amount: $1,922,219 (total costs)
Description: Development of comparative studies of strain using cardiac MRI and 4D cardiac ultrasound.

Agency: NIH 5 U01 MH084241-02 SC1
Title: " 2/8 PROLONGING REMISSION IN DEPRESSED ELDERLY (PRIDE)”
Role: CO-PI (PI: Angel Peterchev, Department of Psychiatry, CUMC)
Period: 1/1/2010 to 7/31/2014
Amount: $210,916 (supports 1 GRA/year under NIH guidelines).

Agency: NIH/NEI - R01 EY021470-01 (PI, R.Smith)
Title:Hyperspectral Imaging of the Normal and Age-Related Macular Degeneration Fundus
Period: 04/01/11 – 03/31/16
Role: Collaborator, w/Paul Sajda
Effort: 5%
Total Award Amount Costs: $2,323,130 ($92,459/year subcontract via NYU to Columbia)

Agency: Philips Research, USA (5 year Po Fellowship Award)
Title: "Modeling of Lung Aspiration Systems for Critical Care”
Role: PI
Period: 1/1/2012 to 12/31/2017
Amount: $278,729 (supports 1 GRA/year, Pol Fellowship Award).

Agency: Philips Research, USA (5 year Po Fellowship Award)
Title: "Compressive Sensing in Ultrasound Imaging”
Role: PI
Period: 1/1/2012 to 12/31/2017
Amount: $278,729 (supports 1 GRA/year, Pol Fellowship Award).

Agency: Massachusetts General Hospital, Boston, Mass (sub-contract)
Title: “Quantitative models for PET/SPECT Reconstruction”
Role: PI
Period: 8/1/12 to 1/30/14
Amount: $52,389/year (support 1 GRA under NIH parent grant guidelines)

Agency: CIMIT CU09-1252and NCIIA 7297-09
Title: “THERAPEUTIC GAMING FOR AUTISTIC CHILDREN”
Role: PI, Supervior for student design team
Period: 4/1/09 - 8/31/14
Amount: $55,000
Description: Design and implement software to support studies on autism.
Doctoral Student Jack Ming Po, Project Director

Philips Research, USA, Fellowship (Antonio Albanese, doctoral student in DBME)
Title: Ventilation & Anesthesia: Real-time CDS & Closed-Loop Control
Role: PI, supervision of doctoral student in collabortion with Dr. Nick Chabat
Period: 9/7/10 – 9/6/14
Amount: $248,000
Description: The project will enhance and augment a CP model by adding more organs and functionality, and by validating and optimizing the computational model. The CP model will be used in the design of high-level closed-loop controllers for ventilator and anesthesia machines, ultimately leading to CDS applications.

Agency: Philips Research, USA (5 year Fellowship Award)
Title: "Compressive Sensing in Ultrasound Imaging”
Role: PI, 5% effort
Period: 1/1/2012 to 12/31/2017
Amount: $278,729 (supports 1 GRA/year).

Agency: Coulter Foundation
Title: Translational Partnership Program (TP2)
Role: PI (Since July 1, 2012)
Collaborators: Denis Folwer, MD, Department of Surgery, Clinical Co-PI
Orin Herskowitz, Columbia Venture Technologies, Co-PI
Donna See, Coulter Program Director, BME Department
Period: 7/1/11 – 6/30/16
Amount: $5M total award, $1M/year (Several grants are competitively awarded each year to paired SEAS / BME faculty and clinician(s) from CUMC).
EFFORT: 10%
 

FULL LENGTH REFEREED PAPERS

[1]    *A. Laine and C.-G. Roman, “A Parallel Algorithm for Incremental Stereo Matching on SIMD Machines,” IEEE Transactions on Robotics and Automation, vol. 13, 1991, pp. 123-134.

[2]    R. Kiltie and A. Laine, “Visual Texture, Machine Vision and Animal Camouflage,” Trends in Ecology and Evolution, vol. 7, pp. 163-166, 1992.

[3]    *A. Laine, S. Schuler, and V. Girish, “Orthonormal Wavelet Representation for Recognizing Complex Annotations,” Machine Vision and Applications, An International Journal, vol. 6, pp. 110-123, 1993.

[4]    *A. Laine, “Special Issue on Wavelet Theory,” in Journal of Mathematical Imaging and Vision, vol. 3: Kluwer Academic Publishers, 1993.

[5]    *A. Laine and J. Fan, “Texture Discrimination and Classification by Wavelet Packets,” IEEE Transactions on Pattern Analysis and Machine Intelligence, vol. 15, pp. 1186-1191, 1993.

[6]    *A. Laine, S. Schuler, J. Fan, and W. Huda, “Mammographic Feature Enhancement by Multiscale Analysis,” IEEE Transactions on Medical Imaging, vol. 13, pp. 725-740, 1994.

[7]    P. Wunsch and A. Laine, “Wavelet Descriptors for Multiresolution Recognition of Handprinted Characters,” Pattern Recognition, vol. 28, pp. 1237-1249, 1995.

[8]    *A. Laine, W. Huda, B. Steinbach, and J. Honeyman, “Mammographic Image Processing Using Wavelet Processing Techniques,” European Radiology, vol. 5, pp. 518-523, 1995.

[9]    R. Kiltie and A. Laine, “A Wavelet-based Metric for Visual Texture Discrimination with Application to Evolutionary Ecology,” Mathematical Biosciences, vol. 126, pp. 21-39, 1995.

[10]    *A. Laine, J. Fan, and W.Yang, “Wavelets for Contrast Enhancement of Digital Mammography,” IEEE Engineering in Medicine and Biology Magazine, vol. 14, pp. 536-550, 1995.

[11]    D. Ioannou, E. Dugan, and A. Laine, “On the Uniqueness of the Representation of a Convex Polygon by its Hough Transform,” Pattern Recognition Letters, vol. 17, pp. 1259-1264, 1996.

[12]    *A. Laine and J. Fan, “Frame Representations for Texture Segmentation,” IEEE Transactions on Image Processing, vol. 5, pp. 771-783, 1996.

[13]    B. Kalman, W. Reinus, S. Kwasny, A. Laine, and L. Kotner, “Prescreening Entire Mammograms for Masses with Artificial Neural Networks: Preliminary Results,” Academic Radiology, vol. 4, pp. 405-414, 1997.

[14]    X. Zong, A. Laine, and E.Geiser, “Speckle Reduction and Contrast Enhancement of Echocardiograms via Multiscale Nonlinear Processing,” IEEE Transactions on Medical Imaging, vol. 17, pp. 532-540, 1998.

[15]    D. Ioannou, W. Huda, and A. Laine, “Circle Recognition Through a 2D Hough Transform and Radius Histogramming,” Image and Vision Computing, vol. 17, pp. 27-36, 1999.

[16]    C. Chang and A. Laine, “Coherence of Multiscale Features for Contrast Enhancement of Dense Radiographs,” IEEE Transactions on Information Technology in Biomedicine, vol. 3, pp. 32-46, 1999.

[17]    *A. Laine, “Wavelets in Spatial Processing of Biomedical Images,"Annual Review ofBiomedical Engineering, vol.2, pp. 511-550, 2000.

[18]    J.-W. Lin, A. Laine, and S.R. Bergmann, "Improving PET-based Physiological Quantification through Wavelet Denoising," IEEE Transactions on Biomedical Engineering, .vol. 48, No. 2, 2001, pp. 202-212.

[19]    J.-W. Lin, A. Laine, O. Akinboboye , S.R. Bergmann, “Use of Wavelet Transforms in the Analysis of Time-Activity Data from Cardiac PET,”  Journal of Nuclear Medicine, 2001;42:194-200.

[20]    J.-W. Lin, R. Sciacca, R.L. Chou, A. Laine, S.R. Bergmann,  “Quantification of Myocardial Perfusion in Human Subjects using Rubidium-82 and Wavelet-Based Noise Reduction,” Journal of Nuclear Medicine, 2001;42:201-208.

[21]    E. Angelini, A. Laine, S. Takuma, J. Holmes, S. Homma, "Temporal Quantification of LV Volumes by Directional Representations in 3D Ultrasound,"IEEE Transactions on Medical Imaging, June, 2001, vol. 20, pp. 457-469.

[22]    L. Fayad, Y. Jin, A. Laine, Y. Berkmen, G. Pearson, B. Freedman and R. Van Heertum, "Multiscale Adaptive Histogram Equalization for Chest CT Windowing: A Pilot Study," Radiology, 223(3), pp. 845-852, June, 2002.

[23]    Unser, M., Aldroubi, A., Laine, A., “Wavelets in Medical Imaging," Guest Editorial,IEEE Transactions on Medical Imaging,Volume 22, Issue 3, March 2003, pp. 285 -288.

[24]    J. Kalifa, A. Laine and P. Esser, “Regularization inTomographic Reconstruction using Thresholding Estimators,” Special Issue of the IEEE Transaction in Medical Imaging: Wavelet Applications in Medical Imaging, Guest Editors M.Unser, A. Albroubi, A. Laine, June, 2003.Volume: 22, Issue 3, March 2003, pp. 351 -359.

[25]    R. Mekle, E. X. Wu, A. Laine, "MRI Scan Time Reduction through K-Space Data Sharing in Combo Acquisitions with A Spin Echo Sequence", IEEE Transactions on Medical Imaging, Volume: 22, Issue: 7 , July 2003, pp. 806 -823.

[26]    Qi Duan, A. Laine, Elsa Angelini, Gregory Pearson, Jeffrey Holmesand Shunichi Homma, “Segmentation of Real-Time Three-Dimensional Ultrasound for Quantification of Ventricular Function:  A Clinical Study on Right and Left Ventricles,” Ultrasound in Medicine & Biology, September, 2005.

[27]    Atanas Georgiev, Sergey Voobiev, William Edstrom, Ting Song, Andrew Laine, John Hunt and Peter Allen, Automated Streak-Seeding with Micromachined Silicon Tools, Acta Crystallographica Section D, vol.62, Part 9, pp: 1039-1045, 2006.

[28]      Matthew Neimark, Angelos-Aristeidis Konstas , Andrew Laine , John Pile-Spellman,      “Integration of Jugular Venous Return and Circle of Willis in a Theoretical Human Model of    Selective Brain Cooling,” Journal of Applied Physiology, vol. 103, issue5, pp. 1837-1847,  2007.

[29]     Angelos-Aristeidis Konstas, Matthew A. Neimark,Andrew  Laine, and John Pile-Spellman, “A theoretical Model of Selective Cooling using Intracarotid Cold Saline Infusionin the Human Brain,”  Journal of Applied Physiology, vol. 102, pp.1329-1340, 2007.

[30]    Elsa Angelini, Ting Song, Brett Mensh, and Andrew Laine, “Brain MRI Segmentation with Multiphase Minimal Partitioning: A Comparative Study,” International Journal of Biomedical Imaging, vol. 2007, Article ID 10526, 15 pages, 2007.

[31]    Neimark MA, Konstas AA, Laine, AF, Pile-Spellman J, “Integration of Jugular Venous Return and Circle of Willis in a Theoretical Human Model of Selective Brain Cooling,”Journal of Applied Physiology,103:1837-1847, November 2007.

[32]    Neimark MA, Konstas AA, Choi JH, Laine AF, Pile-Spellman J, “Brain Cooling Maintenance with Cooling Cap following Induction with Intracarotid Cold Saline Infusion: A Quantitative Model,”Journal of Theoretical Biology, vol. 253, issue 2, pp. 333-344,June 2008
.
[33]    Ravi Bansal, Lawrence H. Staib, Andrew F. Laine, Dongrong Xu, Jun Liu, and Bradley S. Peterson, “Calculation of the Confidence Intervals for Transformation Parameters in the Registration of Medical Images,” vol.13, no.2, pp.215-233, 2009.

[34]    A. R. Kherlopian, T. Song, Q. Duan, M. A. Neimark, M. J. Po, J. K. Gohagan and A. F. Laine, "A review of imaging techniques for systems biology", BMC Systems Biology, vol. 2, no. 74, pp. 1-18, 2008.

35]     Ravi Bansal, Lawrence H. Staib, Dongrong Xu, Andrew F. Laine, Jason Royal, and Bradley S. Peterson, “Using Perturbation Theory to Compute the Morphological Similarity of Diffusion Tensors,” IEEE Transactions on Medical Imaging, vol. 27, issue 5, pp. 589-607, May 2008.

[36]    Q Duan, E Angelini, S Herz, C Ingrassia, K Costa, J Holmes, S Homma, A Laine, “Region-Based Endocardium Tracking on Real-Time Three-Dimensional Ultrasound,” Ultrasound in Medicine and Biology, Vol. 35, No. 2, pp. 256-265, 2008.

[37]    Andrew F. Laine, “In the Spotlight: Biomedical Imaging,” IEEE Reviews in Biomedical Engineering, vol. 1, pp. 4-7, IEEE Press, 2008.

[38]    S. X. Liu, C. Imielinska, A. F. Laine, W. S. Millar, E. S. Connolly, and A. L. D’Ambrosio, “Asymmetry Analysis in Rodent Cerebral Ischemia Models,” Academic Radiology, vol. 15, no. 9, pp. 1181-1197, 2008.

[39]    T. Song, A. F. Laine, Q. Chen, H. Rusinek, B. Louisa, R. Lim, L. Gerhard, R. Kroeker, L. Vivian, " Optimal K-Space Sampling for Dynamic Contrast-Enhanced MR Imaging with an Application to MR Renography", Journal of Magnetic Resonance in Medicine, vol. 61, issue 5, pp. 1242-1248, 2009.

[40]     Q. Duan, E. D. Angelini, A.F. Laine, "Surface Function Actives", J. Vis. Commun. Image R., vol. 20, no. 7, pp. 478-490, 2009.

[41]    R. Bansal, L. H. Staib, A. F. Laine, D. Xu, J. Liu, and B. S. Peterson, "Calculation of the Confidence Intervals for Transformation Parameters in the Registration of Medical Images", Medical Image Analysis, vol. 13, no. 2, pp. 215-233, 2009.

[42]    Ting Song, Vivian S Lee, Qun Chen, Henry Rusinek, Andrew F Laine, " An Automated Three Dimensional plus Time Registration Framework for Dynamic MR Renography ", J Visual Communication and Image Representation, vol.21, no. 1, pp.1-8, 2010.

[43]    A. F. Laine, "In the Spotlight: Biomedical Imaging", IEEE Reviews in Biomedical Engineering, vol. 2, pp. 6-8, December, IEEE Press, 2009.

[44]    N. Lee, A. F. Laine, G. Márquez, J. M. Levsky, and J. K. Gohagan, " Potential of Computer-Aided Diagnosis to Improve CT Lung Cancer Screening", IEEE Reviews in Biomedical Engineering, vol. 2, pp. 136-146, 2009.

[45]     R.T. Smith, N.L. Gomes, G. Barile, M. Busuioc, N. Lee, A.F. Laine, " Lipofuscin & Autofluorescence Metrics in progressive STGD", Invest. Ophthalmol. Vis. Sci., vol. 50, pp. 3907-3914, 2009.

[46]    Sheena Xin Liu , John Kender, C . Imielinska, A. F. Laine , “Partial Surface Matching in the Correction of Misalignment of 3D Brain Images”, in press, Journal of NeuroImaging, 2009.

[47]    J. Chen, J. Tian, N. Lee, J. Zheng, R.T. Smith, A.F. Laine, "A Partial Intensity Invariant Feature Descriptor for Multimodal Retinal Image Registration", IEEE Transactions of Biomedical Engineering, vol. 57, no. 7, pp. 1707-1718, 2010.

[48]    T. Song, V. S. Lee, Q. Chen, H. Rusinek, A. F. Laine, "An Automated Three Dimensional plus Time Registration Framework for Dynamic MR Renography ", J. Visual Communication and Image Representation, vol. 21, no. 1, pp. 1-8, 2010.

[49]     R Theodore Smith, Mahsa A Sohrab, Nicole Pumariega, Yue Chen, Jian Chen, Noah Lee,     Andrew Laine, " Dynamic soft drusen remodelling in age-related macular degeneration", Br J Ophthalmol doi:10.1136/bjo.2009.166843, 2010.

[50]     Sheena Xin Liu, C.Imielinska, John Kender, A. F. Laine, "Automatic Misalignment Correction of Neuroimages using Surface Symmetry Priors", Journal of NeuroImaging , Vol. 32, No. 3, 2010.

[51]    Fei Wang, Noah Lee, Jianying Hu, Jimeng Sun, Shahram Ebadollahi, Andrew F Laine "A Framework for Mining Signatures from Event Sequences and Its Applications in Healthcare Data", IEEE Transactions on Pattern Analysis and Machine Intelligence, 2013.

[52]  Won Hee Lee, Z. D. Deng, T. S. Kim, S. H. Lisanby, A. V. Peterchev, Andrew F Laine, "Regional electric field induced by electroconvulsive therapy in a realistic finite element  head model: influence of white matter anisotropic conductivity", NeuroImage, vol. 59,  no. 3, pp. 2110-2123, 2012.

[53]  Amin Katouzian, Stephane Carlier, Jasjit Suri, Nassir Navab, Andrew F Laine, Elsa Angelini "A State of The Art Review on Segmentation Algorithms in Intravascular Ultrasound (IVUS) Images", IEEE Transactions on Information Technology in BioMedicine, vol. 16, No 5, pp. 823 – 834, 2012

[54]  Amin Katouzian, Athanasios Karamalis, Abouzar Eslami, Elisa Konofagou, Babak Baseri, Stephane Carlier, Andreas Koenig, Nassir Navab, Andrew Laine "Iterative Self-Organizing Atherosclerotic Tissue Labeling in Intravascular Ultrasound Images and Comparison with Virtual Histology",  IEEE Transactions on Biomedical Engineering, 2012.

[55]    Fei Wang, Noah Lee, Jianying Hu, Jimeng Sun, Shahram Ebadollahi, Andrew F     Laine "A Framework for Mining Signatures from Event Sequences and Its  Applications in Healthcare Data", IEEE Transactions on Pattern Analysis and     Machine Intelligence, Volume: 35, Issue: 2, 2013.

[56]    David Elad, Pavel Kozlovsky, Omry Blum, Andrew F. Laine, Ming Jack Po, Eyal     Botzer, Shaul Dollberg, Mabel Zelicovich, "Biomechanics of milk extraction during     breast-feeding", Proceedings of the National Academy of Sciences (PNAS), in press,     March, 2014.

[57]    Yrjö Häme, Elsa Angelini, Eric Hoffman, Graham Barr, Andrew F Laine, "Adaptive     quantification and longitudinal analysis of pulmonary emphysema with a hidden     Markov measure field model", IEEE Transactions on Medical Imaging (Accepted,     April 4, 2014).

[58]    Auranuch Lorsakul, Quanzheng Li, Christopher Hoog, Yoann Petibon and Georges El     Fakhri, “4D Mathematical model observer for lesion detection on respiratory-gated PET     imaging,” Journal of Nuclear Medicine. 2013; 54 (Supplement 2):538.

[59]    Auranuch Lorsakul, Quanzheng Li, Cathryn M. Trott, Christopher Hoog, Yoann Petibon,      Jinsong Ouyang, Andrew F. Laine, and Georges El Fakhri “Four-Dimensional Numerical Observer for Lesion Detection in Respiratory-Gated PET,”    Medical Physics, accepted for publication, March 2014.

[60]    Lorsakul, Auranuch; El Fakhri, Georges; Guo, Ning; Yen, Ruoh­ Fang; Normandin, Marc D.;     Alpert, Nathaniel M.; Laine, Andrew F.; Li, Quanzheng, "A Numerical     Observer     for Task­Based Assessment on Kinetic Parametric Imaging,” J Nucl Med.     2014: 48.

 

REFEREED FULL LENGTH PROCEEDINGS PAPERS

[1]    G.C. Roman, A.F. Laine, K.C. Cox, “Interactive Complexity Control and High-Speed Stereo Matching,”Computer Vision and Pattern Recognition, 1988. Proceedings CVPR '88., Computer Society Conference on , 5-9 June 1988, Pages:171 - 176.

[2]    *A. Laine, W. Ball, and A. Kumar, “A Multiscale Approach for Recognizing Complex Annotations in Engineering Documents,” Proceedings of IEEE Computer Society Conference on Computer Vision and Pattern Recognition, IEEE Press, 1991, pp. 749-750.

[3]    *A.F. Laine, “Multiscale Wavelet Representations for Mammographic Feature Analysis,”in Proceedings of the National Cancer Institute Breast Imaging Workshop: State-of-the-Art and New Technologies, Image Enhancement Techniques: Computer Science, Bethesda, MD, September 4-6,1991, pp. 749-750.

[4]    Z. Jing, Y. Zheng, W. Huda, A.F. Laine, J. Fan, and Y. Xing,“Quantitative Evaluation of Wavelet-Based Image Processing Algorithms,in Wavelet Applications in Signal and Image Processing II,”Proceedings of SPIE, San Diego, CA, July 27-29, 1994, vol. 2303, pp. 569-578.

[5]    Y. Xing, W. Huda, A.F. Laine, and J. Fan, “Simulated Phantom Images for Optimizing Wavelet-Based Image Processing Algorithms in Mammography,”in Mathematical Methods in Medical Imaging III, Proceedings of SPIE, San Diego, CA, July 25-26, 1994, vol. 2299, pp. 207-217.

[6]    *A.F. Laine, M. Lewis, and F. Taylor,“A Wavelet Based Mammographic System,”
Proceedings of the IEEE International Conference on Acoustics, Speech and Signal Processing, Adelaide, Australia, April 19-22, 1994, vol. 5, pp. 21-24.

[7]    *A. Laine and S. Schuler, “Hexagonal Wavelet Representations for Recognizing Complex Annotations,” Proceedings of IEEE Conference on Computer Vision and Pattern Recognition, IEEE Press, 1994, pp. 740-745.

[8]    I. Koren, A. Laine, J. Fan, and F. Taylor, “Edge Detection in Echocardiographic Image Sequences by 3D Multiscale Analysis,” Proceedings ofIEEE International Conference on       Image Processing, IEEE Press,1994, vol.1, pp. 288-292.

[9]    *A. Laine, J. Fan, and S. Schuler, “A Framework for Contrast Enhancement by Dyadic Wavelet Analysis,” in Digital Mammography, S. M. A. A. G. Gale, D. R. Dance, and A.Y. Cairns, Ed. Amsterdam, The Netherlands: Elsevier, 1994, pp. 91-100.

[10]    *A. Laine, J. Fan, and S. Schuler, “Contrast Enhancement by Dyadic Wavelet Analysis,” Proceedings of 16th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, IEEE Press, 1994, vol.1, pp. 10a-11a.

[11]    *A.  Laine and F. Taylor, “A Wavelet Based Mammographic System,” Proceedings ofIEEE International Conference on Acoustics, Speech and Signal Processing, IEEE Press, 1994, vol.5, pp. 21-24.

[12]    I. Koren, A. Laine, and F. Taylor, “Image Fusion using Steerable Dyadic Wavelet Transform,” Proceedings of the IEEE International Conference on Image Processing, IEEE Press,1995, vol.3, pp. 232-235.

[13]    D. Benn, J. Pettigrew, M. Shim, A. Laine, A. Mancuso, C. Bose, and H. Stambuck, “A Pilot Study of Automated Knowledge-Based Recognition of Facial Bones form Axial CT Slices,” Proceedings of International Symposium on Computer and Communication System for Image Guided Diagnosis and Therapy, Computer Assisted Radiology, Springer-Verlag, 1995,  pp.1021-1027.

[14]    *A. Laine and X. Zong, “Border Identification of Echocardiograms via Multiscale Edge Detection and Shape Modeling,” Proceedings ofIEEE International Conference on Image Processing, IEEE Press, 1996, vol.3, pp. 287-290.

[15]    I. Koren, A. Laine, F. Taylor, and M. Lewis, “Interactive Wavelet Processing and Techniques Applied to Digital Mammography,” Proceedings of theIEEE International Conference on Acoustics, Speech, and Signal Processing, IEEE Press, 1996, vol.3, pp. 1415-1418.

[16]    D. Benn, J. Pettigrew, M. Shim, A. Laine, A. Mancuso, and H. Stambuck, “Automatic Image Recognition of Facial Bones,” Proceedings of theComputer Assisted Radiology, Springer-Verlag,1996, pp. 943-948.

[17]    G. Qu, W. Huda, A.F. Laine, B.G. Steinbach, J.C. Honeyman, “Can Digital Mammography Improve Low Contrast Lesion Detection?,”in Digital Mammography '96, Proceedings of the 3rd International Workshop on Digital Mammography, Chicago, U.S.A., 9-12 June 1996, K. Doi, M. L. Giger, R. M. Nishikawa, and R. A. Schmidt, Editors, Amsterdam, The Netherlands: Elsevier, 1996, pp. 451-454.

[18]    *A.F. Laine, W. Huda, D. Chen, and J. Harris, “Segmentation of Masses using Continuous Scale Representations,”in Digital Mammography '96, Proceedings of the 3rd International Workshop on Digital Mammography, Chicago, U.S.A., 9-12 June 1996, K. Doi, M. L. Giger, R. M. Nishikawa, and R. A. Schmidt, Editors, Amsterdam, The Netherlands: Elsevier, 1996, pp. 447-450.

[19]    *A.F. Laine, “Wavelet Processing Techniques for Enhancement and Computer Aided Diagnoses of Digital Mammography,”Medical and Biological Engineering and Computing, vol. 34, SUPPL. 1, pp. 419, 1996.

[20]    X. Zong, A. Meyer-Baese, and A. Laine, “Multiscale Segmentation Through A Radial Basis Neural Network,” Proceedings ofIEEE International Conference on Image Processing, IEEE Press, 1997, vol.3, pp. 400-403.

[21]    C. Chang and A. Laine, “Enhancement of Mammograms from Oriented Information,” Proceedings of the IEEE International Conference on Image Processing, IEEE Press, 1997, vol.3, pp. 524-527.

[22]    M. Shim and A. Laine, “Overcomplete Lifted Representations for Multiscale Feature Analysis,” Proceedings of IEEE International Conference on Image Processing, IEEE Press, 1998, vol.2, pp. 242-246.

[23]    I. Koren, A. Laine, and F. Taylor, “Enhancement via Fusion of Mammographic Features,” Proceedings of IEEE International Conference on Image Processing, IEEE Press, 1998, vol.2, pp. 722-726.

[24]    C. Chang, D. Chen, and A. Laine, “Detection of Subtle Masses in Mammography via Multiscale Analysis at Arbitrary Scales,” Proceedings of Third Asian Conference on Computer Vision, IEEE Press, 1998, vol.1, pp. 192-199.

[25]    E. Angelini, A. Laine, S. Takuma, and S. Homma,“Directional Representations of 4D Echocardiography for Temporal Quantification of LV Volumes,”Proceedings of Medical Image Computing and Computer-Assisted Intervention (MICCAI),Springer-Verlag, 1999, pp. 430-440.

[26]    I. Koren, A.F. Laine, S.J. Smith, E.L. Nickoloff and F. Taylor, “Visualization of Memmography via Fusion of Enhanced Features,”
in M. Doi (Editor), the 1stInternational Workshop on Computer-Aided Diagnosis, Elsevier Science, Amsterdam, 1999, pp. 287-303.

[27]    R. Mekle, A.F. Laine, S.J. Smith, C. Singer, T. Koenigsberg and M. Brown, “Evaluation of a Multiscale Enhancement Protocol for Digital Mammography,” Proceedings of SPIE - The International Society for Optical Engineering, vol. 4119, pp. 1038-1049, San Diego, 2000.

[28]    J. Kalifa, A.F. Laine, P.D. Esser, “Image Reconstruction from Tomographic Data using Thresholding Estimators in an Orthogonal Basis,”Proceedings of the SPIE - Wavelet Applications in Signal and Image Processing VIII, vol. 4119, pp. 576-585, San Diego, 2000.

[29]    J. Kalifa, Y. Jin, A.F. Laine, P.D. Esser, “Tomographic Reconstruction with Non-linear Diagonal Estimators,”Proceedings of European Association of Nuclear Medicine, vol.4119, pp. 576-586, September 2000, Paris, France.

[30]    E. Angelini, A. Laine, J. Donis, D. Gersony, and S. Homma,“Quantification of Right and Left Ventricular Function with Real-Time Three-Dimensional Ultrasound,” Proceedings of the 23rdAnnual International Conference of the IEEE Engineering in Medicine and Biology Society, vol. 3, pp. 2587-2590, Istanbul, Turkey, 2001.

[31]    R. Mekle, E. X. Wu, A. Laine, “MRI Scan Time Reduction through K-Space Data Sharing in Combo Acquisitions with a Spin Echo Sequence”, Proceeding of the 23rd Annual International Conference of the IEEE Engineering in Medicine and Biology Society, vol. 3, Istanbul, Turkey, 2001.

[32]    J. Kalifa, A.F. Laine, P.D. Esser, “Regularization in Tomographic Reconstruction using Thresholding Estimators,”Proceedings of SPIE - Wavelet Applications in Signal and Image Processing IX, vol. 4478, pp. 63-74, San Diego, 2001.

[33]    E. Angelini, J. Kalifa, and A. Laine, “Harmonic  Multiresolution Estimators for Denoising and Regularization of SPECT-PET Data,”Proceedings of the IEEE International Symposium on Biomedical Imaging: Macro to Nano, July 7-10, 2002, Washington, D.C.

[34]    E.D. Angelini, Hamming, D., S. Homma, Holmes, J.W., A.F. Laine, “Comparison of Segmentation Methods for Analysis of Endocardial Wall Motion with Real-Time Three-Dimensional Ultrasound,”Computers in Cardiology, vol. 29, September 22-25, 2002, pp. 609 -612.

[35]    E. Angelini, J. Holmes, A. Laine, S. Homma, “Segmentation of RT3D Ultrasound with Implicit Deformable Models without Gradients”, Proceedings of the 3rd International Symposium on mage and Signal Processing and Analysis (ISPA 2003), vol. 2, pp. 711-716,September 18-20, 2003, Rome, Italy.

[36]    Y. Jin, E. Angelini, S. Mangla, In Sup Choi, R. Kemkers, J. Timmer, A. Laine“Multiscale Denoising and Enhancement of 3D Rotational X-ray Imaging for Percutaneous Vertebroplasty,” Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology,vol. 1, pp. 782-785, September 17-22, 2003, Cancun, Mexico.

[37]    E. Angelini, T. Song, Q. Quan, A. Laine, “A comparison of Interpolation Methods for 3D Cardiac Ultrasound Imaging,”Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology, vol. 1,September 17-22, 2003, Cancun, Mexico.

[38]    Y. Jin,C. Imielinska and A. Laine,  “A Clinical Study of Adipose Tissue Quantification by Whole Body MRI: Segmentation and Evaluation”, Proceedings of the Medical Image Computing and Computer-Assisted Intervention (MICCAI 2003), Toronto, Canada, November 2003.

[39]    Y. Jin,Peter Esser and A. Laine, “SPECT/PET Image Denoising Using Cross-Scale Regularization,” Proceedings of the Medical Image Computing and Computer-Assisted Intervention (MICCAI 2003), Toronto Canada, November 2003.

[40]    E. Angelini, Y. Jin, P. Esser, R. Van Heertum, A. Laine, “Fusion of Brushlet and Wavelet Denoising Methods for Nuclear Images,” Proceeding of the 2nd IEEE International Symposium on Biomedical Imaging: Macro to Nano, vol. 2, pp. 1187-1191, April 15-18, 2004, Arlington, VA.

[41]    E. Angelini, R. Otsuka, S. Homma, A. Laine, “Comparison of Ventricular Geometry for Two Real Time 3D Ultrasound Machines with Three Dimensional Level Set,”Proceeding of the 2nd IEEE International Symposium on Biomedical Imaging: Macro to Nano, vol. 2, pp. 1323- 1326, April 15-18, 2004, Arlington, VA.

[42]    Albert Max Lai, Jason Nieh, A. Laine, Justin Starren, “Remote Display Performance for Wireless Healthcare Computing,”Medinfo 2004, vol. 11, issue Pt 2, pp. 1438-1442, September 7-11, 2004, San Francisco, CA.

[43]    E. D. Angelini, T. Song, B. D. Mensh, A. Laine, “Segmentation and Quantitative Evaluation of Brain MRI Data with a Multi-Phase Three-Dimensional Implicit Deformable Model,”Proceedings of SPIE - The International Society for Optical Engineering:Medical Imaging 2004, vol. 5370 I, pp. 526-537, February 16-19, 2004., San Diego,  CA  USA.

[44]    Q. Duan, E. D. Angelini, A. Laine, “Assessment of Fast Anisotropic Diffusion and Scan Conversion of Real-Time Three-Dimensional Spherical Ultrasound Data for Visual Quality and Spatial Accuracy,”Proceedings of SPIE - The International Society for Optical Engineering:Medical Imaging 2004, vol. 5370 I, February 16-19, 2004., San Diego,  CA  USA.

[45]    E. D. Angelini, T. Song, B. D. Mensh, A. Laine, “Multi-Phase Three-Dimensional Level Set Segmentation of Brain MRI, ”Proceedings of the Medical Image Computing and Computer-Assisted Intervention (MICCAI 2004), Saint-Malo, France, 2004.

[46]    T. Song, E. D. Angelini, B. D. Mensh, and A. Laine, ”Comparison Study of Clinical 3D MRI Brain Segmentation Evaluation,” Proceedings of the26th Annual International Conference of the IEEE Engineering in Medicine and Biology, vol. 26 III, pp. 1671-1674, September 1-5, 2004, San Francisco, CA, United States.

[47]    Y. Wang, E. D. Angelini, D. H. Kim, and A. Laine, “High-Speed Recognition of Micro-Array Genomic Images Using Multi-Scale Representations,”Proceedings of the International Conference on Structural Genomics, Washington, DC, USA, 2004.

[48]    Y. Jin, P. Esser, T. Aikawa, B. Kuang, S. Duan, and A. Laine, “Regularization of PET Reconstruction using Multi-Scale Adaptive Thresholding,”Proceedingsof theAnnualInternational Conference of the IEEE Engineering in Medicine and Biology, vol. 26 III, pp.1616-1619,September 1-5, 2004, San Francisco, CA, United States.

[49]    A. Georgiev, P. K. Allen, W. Edstrom, J. Hunt, T. Song, and A. Laine, “Robotic Protein Crystal Streak Seeding Using Silicon Microtools,”Proceedings of theInternational Conference on Structural Genomics, Washington, DC, USA, 2004.

[50]    E. D. Angelini, Y. Wang, and A. Laine, “Classification of Micro Array Genomic Images with Laplacian Pyramidal Filters and Neural Networks,”Proceedings of the Workshop on Genomic Signal Processing and Statistics (GENSIPS), Baltimore, Maryland, USA, 2004.

[51]    Q. Duan, E. D. Angelini, S. L. Herz, O. Gerard, P. Allain, C. M. Ingrassia, K. D. Costa, J. W. Holmes, S. Homma, and A. Laine, “Tracking of LV Endocardial Surface on Real-Time Three-Dimensional Ultrasound with Optical Flow,”Proceedings of the3rdInternational Conference on Functional Imaging and Modeling of the Heart (FIMH 2005), Barcelona, Spain, June 2-5, 2005.

[52]    Q. Duan, E. D. Angelini, S. L. Herz, C. M. Ingrassia, O. Gerard, K. D. Costa, J. W. Holmes, and A. Laine, “Evaluation of Optical Flow Algorithms for Tracking Endocardial Surfaces on Three-Dimensional Ultrasound Data,”  Proceedings of SPIE - The International Society for Optical Engineering:Medical Imaging 2005, vol. 5750, Art. No. 19, pp. 159-169, San Diego, CA, USA, 2005.

[53]    A. Georgiev, P. K. Allen, T. Song, A. Laine, W. Edstrom, and J. Hunt, “Microrobotic Streak Seeding For Protein Crystal Growth,”Proceedings of theRobotics: Science and Systems, Cambridge, MA, 2005.

[54]    G. Schoonenberg, M. Schrijver, Q. Duan, R. Kemkers, and A. Laine, “Adaptive Spatial-Temporal Filtering Applied to X-Ray Fluoroscopy Angiography,”Proceedings of SPIE: Medical Imaging 2005: Visualization, Image-Guided Procedures, and Display, vol. 5744, issue II, Art. No. 100, pp. 870 877, February 13-15, 2005, San Diego, CA, USA.

[55]    T. Song, V. S. Lee, H. Rusinek, J. B. Sajous, A. F. Laine , “Registration and Segmentation of Dynamic Three-dimensional MR Renography Based on Fourier Representations and K-Means Clustering”, Proceedings of the 13th International Society for Magnetic Resonance in Medicine (ISMRM 2005), May7-13, 2005, Miami Beach, Florida, USA. pp442 (2266), 2005.

[56]    Qi Duan, Elsa Angelini, Olivier Gerard, Shunichi Homma, Andrew Laine, “ComparingOptical-Flow Based Methods for Quantification of Myocardial Deformations on RT3D Ultrasound,” Proceedings of the 2006 IEEE International Symposium on Biomedical Imaging:From Nano to Macro, April 6-9, 2006, Arlington, Virginia,USA, pp.173-176, 2006.

[57]    Qi Duan, Daniel Moses, Monvadi B. Srichai, Vinay M. Pai, Andrew F.Laine, “A Semi-Automatic Ventricular Border Segmentation Package Based on Multi-PhaseLevelset Segmentation,” Proceedings of the 14th Scientific Meeting & Exhibition (ISMRM),May 6-12, 2006, Seattle, Washington, USA, pp.1014, 2006.

[58]    Xin Liu, Celina Imielinska, Andrew Laine, E. Sander Connolly, Anthony L. D'Ambrosio, “Symmetry Identification UsingPartialSurface Matching and Tilt Correction in 3D Brain Images,”Proceedings of the 28th Annual International Conference IEEE Engineering in Medicine and Biology Society (EMBS),vol. 1, pp. 1056-1060, August 30-September 3, 2006, New York City, USA.

[59]    Angelos-Aristeidis Konstas, Matthew A. Neimark, Andrew F. Laine, and John Pile-Spellman,
“Selective Brain Cooling using Intracarotid Cold Saline Infusion in Humans: Theoretical Model and Practical Implications,”Proceedings of the 28th Annual International Conference IEEEEngineering inMedicine and Biology Society (EMBS), August 30-September 3, 2006, New York City.

[60]    Qi Duan, Elsa Angelini, Shunichi Homma, Andrew Laine, “TrackingEndocardium Using Optical Flow along Iso-Value Curve,” Proceedings of theIEEE 2006 International Conference of the Engineering in Medicine and Biology Society, August 30-Sept. 3, 2006, New York, NY, USA, pp. 707-710, 2006.

[61]    Ting Song, Vivian S. Lee, Henry Rusinek, Samson Wong, and Andrew F. Laine, “An Iterative Framework for Registration and Segmentation of Dynamic Three-Dimensional MR Renography,”Proceedings of the14thInternational Society for Magnetic Resonance in Medicine(ISMRM), pp. 831, 2006.

[62]    Elsa Angelini, Ting Song, and Andrew Laine,“Homogeneity Measures for Multiphasse Level Set Segmentation of Brain MRI,”, Proceedings of the International symposium on Biomedical Imaging (ISBI), pp. 746-749, 2006.

[63]    Qi Duan, Elsa Angelini, Shunichi Homma, Andrew Laine, “Validationof Optical-Flow for Quantification of Myocardial Deformationson Simulated RT3D Ultrasound,”Proceedings of the IEEEInternationalSymposium on Biomedical Imaging (ISBI):From Nanoto Macro, April 12-15, 2007, Arlington, Virginia, USA.

[64]    T. Song, V. S. Lee, H. Rusinek, S. Wong, and A. F. Laine, “Four Dimensional MR Image Analysis of Dynamic Renography,”Proceeding of the 28th AnnualInternational Conference IEEE Engineering in Medicine and Biology Society (EMBS), New York, NY, USA, pp. 3134-3137,August 30 - September 3, 2006.

[65]    TingSong, Vivian S. Lee, Henry Rusinek, Samson Wong, and Andrew F. Laine, “Integrated Four Dimensional Registration and Segmentation of Dynamic Renal MR Images,” Proceedings of the 9th International Medical Image Computing and Computer-Assisted InterventionConference (MICCAI), Oct. 1-6, 2006, Copenhagen, Denmark, LNCS4191, pp. 758-765.

[66]    T. Song, A. F. Laine, V. S. Lee, J. Ko, H. Pass, D. Nonaka, K.Zhang, and Q. Chen, “Automatic Registration of Lung Nodules on 4D Dynamic Contrast Enhanced MR Images,” Proceedings of theJoint Annual Meeting ISMRM-ESMRMB, Berlin, Germany, 19-25 May 2007.

[67]    T. Song, A. F. Laine, Q. Chen, H. Rusinek, N. Oesingmann, L.Bokachev, and V. S. Lee, “Quantitative Simulation Approach for Optimization of Spiral K-Space-Sampled Time-Resolved Contrast-EnhancedMRA,” Proceedings of the Joint Annaul MeetingISMRM-ESMRMB, Berlin, Germany,19-25 May 2007.

[68]    T. Song, A. F. Laine, Q. Chen, H. Rusinek, N. Oesingmann, L.Bokachev, and V. S. Lee, “A New Spiral K-Space Sampled Time-Resolved MR Optimization Approach for 4D MR Renography,”Proceedings of the Joint Annaul ISMRM-ESMRMB, Berlin, Germany, 19-25 May 2007.

[69]    Qi Duan, Elsa Angelini, Philippe Moireau, Dominique Chapelle, Andrew Laine,“Simulation of3D Ultrasound with a Realistic Electro-Mechanical Model of the Heart”, Proceedings of the 4thInternational Conference on Functional Imaging and Modeling of the Heart (FIMH 2007),June 7-9, 2007, Salt Lake City, Utah.

[70]    Qi Duan, Andrew F. Laine, Vinay M. Pai, “On the Limits of Image Noise Suppression inHigh-Speed Cardiac MR Parallel Acquisition,”Proceedings of the15th Scientific Meeting & Exhibition(ISMRM), May 19-25, 2007, Berlin, Germany.

[71]    Qi Duan, Guy Shechter, Luis F. Gutierrez, Douglas Stanton, Lyubomir Zagorchev, Andrew F. Laine, Daniel Elgort, “Augmenting CT Cardiac Roadmaps with Segmented StreamingUltrasound,” Proceedings of theSPIE International Symposium:Medical Imaging 2007, SanDiego, CA, USA, February, 2007.

[72]    Noah Lee, Andrew F. Laine, and R.Theodore Smith, “A HybridSegmentation Approach for Geographic Atrophy in Fundus Auto-Fluorescence Images for Diagnosis of Age-Related Macular Degeneration,” Proceedings of the29th Annual International Conference IEEE Engineering in Medicine and Biology Society (EMBC), vol. 2007, pp. 4965-4968, August, 2007, Lyon, France.

[73]    R. F. Lee, T. Song, R. Xue, A. F. Laine, “Wavelet-Based Mode-Scanning Excitation (MSE) for Selective Excitation at High Field,”Proceedings of the 15th International Society of Magnetic Resonance in Medicine, Berlin, Germany, pp. 1052, 19-25, May 2007.  

[74]    A. Shaikh, B. Taouli, T. Song, H. Youn, G. Fielding, A. F. Laine, C. Ren, “Quantification of Liver Volume, Liver Fat Fraction and Subcutaneous-Visceral Fat Changes with 3T MRI After Hypocaloric Diet in Morbidly Obese Patients,” Proceedings of the 15th International Society of Magnetic Resonance in Medicine, Berlin, Germany, pp. 2702, 19-25 May 2007.

[75]    Neimark MA, Konstas AA, Choi JH, Laine AF, Pile-Spellman J, “Local Control of Temperature in a Theoretical Human Model of Selective Brain Cooling,”Proceedings of theAnnual International Conference of the IEEE Engineering in Medicine and Biology Society., vol. 2007, pp. 6349-6352, August 2007.

[76]    Neimark MA, Konstas AA, Choi JH, Laine AF, Pile-Spellman J, “The Role of Intracarotid Cold Saline Infusion on a Theoretical Brain Model Incorporating the Circle of Willis and Cerebral Venous Return,” Proceedings of theAnnual International Conference of the IEEE Engineering in Medicine and Biology Society, vol. 2007, pp. 1140-1143, August 2007.

[77]    Noah Lee, Andrew F. Laine, and Theodore R. Smith, “Learning Non-Homogeneous Textures and the Unlearning Problem with Application to Drusen Detection in Retinal Images,”, Proceedings of the5th IEEE International Symposium on Biomedical Imaging: From Nano to Macro (ISBI 2008), Art. No. 4541221, pp. 1215-1218, May 14-17, 2008, Paris France.

[78]    Qi Duan, Elsa Angelini, Shunichi Homma, Andrew Laine, “Real-Time Segmentation of 4D Ultrasound by Active Geometric Functions,”Proceedings of the5th IEEE International Symposium on Biomedical Imaging: From Nano to Macro (ISBI 2008), Art. No. 4540975, pp. 233-236, May 14-17, 2008, Paris, France.

[79]    T. Song, V. S. Lee, H. Rusinek, Q. Chen, A. Laine, Segmentation of 4D MR Renography Images Using Temporal Dynamics in a Level Set Framework, Proceedings of the5th IEEE International Symposium on Biomedical Imaging: From Nano to Macro (ISBI 2008), Art. No. 4540926, pp. 37-40, May 14-17,2008, Paris, France.

[80]    Noah Lee, Huseyin Tek, and Andrew F. Laine, “True-False Lumen Segmentation of Aortic Dissection using Multi-Scale Wavelet Analysis and Generative-Discriminative Model Matching,”Proceedings of the SPIE Medical Imaging: Computer-Aided Diagnosis, vol: 6915, Art. No. 69152V, February 19-21, 2008, San Diego 2008.  

[81]    Ming Jack Po, George DeTitta, Andrew Laine, “The Automated Recognition of Protein Crystal Images by Feed-forward Neural Network,”Workshop on Bio-Image Informatics: Biological Imaging, Computer Vision and Data Mining, Santa Barbara, CA, US, Jan 17-18, 2008.

[82]    Jian Chen, Jie Tian, R. Theodore Smith, and Andrew F. Laine, “A Novel Registration Method for Retinal Images Based on Local Features,” Proceedings of the30th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, pp. 2242-2245,Vancouver,Canada, August 2008.

[83]    Noah Lee, Andrew F. Laine, and R. Theodore Smith, “Coarse to Fine Segmentation of Stargardt Rings using an Expert Guided Dual Ellipse Model,”Proceedings of the30th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, pp. 2250-2253, Vancouver, Canada, August 2008.

[84]    M. Po, A. F. Laine, " Leveraging Genetic Algorithm and Neural Networks in Automated Protein Crystal Recognition", Proceeding of 30th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC), pp. 1926-1929, Vancouver, Canada, 2008.

[85]    Amin Katouzian, Babak Baseri, Elisa E. Konofagou, Andrew F. Laine, “Texture-Driven Coronary Artery Plaque Characterization Using Wavelet Packet Signatures,” Proceedings of the5th IEEE International Symposium on Biomedical Imaging: From Nano to Macro (ISBI 2008), Art. No. 4540966, pp. 197-200, May 14-17, 2008, Paris, France, 2008.

[86]    N. Lee, R. T. Smith, A. F. Laine, " Interactive Segmentation for Geographic Atrophy in Retinal Fundus Images", Proceedings of Asilomar Conference on Signals, Systems and Computers, IEEE Signal Processing Society , 2008.

[87]    Amin Katouzian, Babak Baseri, Elisa E. Konofagou, Andrew F. Laine, “Automatic Detection of Blood versus non-Blood Regions on Intravascular Ultrasound (IUVUS) Images Using Wavelet Packet Signatures,”Proceedings of SPIE: Medical Imaging 2008: Ultrasonic Imaging and Signal Processing, vol. 6920, Art. No. 69200H,  San Diego, CA, February 17-18, 2008.

[88]    A. Katouzian, B. Baseri, E. E. Konofagou, and A. F. Laine, “An Alternative Approach to Spectrum-Based Atherosclerotic Plaque Characterization Techniques Using Intravascular Ultrasound (IVUS) Backscattered Signals,”Proceedings of the2nd MICCAI Workshop on Computer Vision for Intravascular and Intracardiac Imaging (MICCAI 2008), New York, NY USA, 2008.

[89]    R Theodore Smith, Nuno Gomes, Mihai Busuioc, Noah Lee, Andrew Laine, “Autofluorescence Image Analysis in Age-related Macular Degeneration (AMD) and Stargardt Disease (STGD)”, Proceedings of the IEEE Signal Processing Society, Asilomar Conference on Signals, Systems and Computers, 2008

[90]    Jesus Caban, Noah Lee, Shahram Ebadollahi, Andrew Laine, Rober DeLaPaz, John R. Kender, “Concept Detection in Brain MR Images using Multi-Modal Information” Proceedings of the Society of Imaging Informatics in Medicine (SIIM) Conference, June 2009, Charlotte, NC, USA.

[91]    N. Lee, J. Caban, S. Ebadollahi, A. Laine, " Interactive Segmentation in Multi-Modal Medical Imagery using a Bayesian Transductive Learning Approach", Proceeding of SPIE Medical Imaging, Florida, USA, Vol. 7260, 72601W, 2009.

[92]    Qi Duan, Elsa D. Angelini , Auranuch Lorsakul, Shunichi Homma,and Andrew F. Laine, “Coronary Occlusion Detection with 4D Optical Flow Based Strain Estimation on 4D Ultrasound Lumen Border Detection of Intravascular Ultrasound via Denoising of Directional Wavelet Representations,” Proceedings of the Functional Imaging and Modeling of the Heart (FIMH 2009), pp. 211-219, Nice, France, June 3-5, 2009.

[93]    N. Lee, A.F. Laine, S. Ebadollahi, R.L. DeLaPaz, " Bayesian Transduction and Markov Conditional Mixtures for Spatiotemporal Interactive Segmentation ", Proceedings of 4th International IEEE EMBS Conference on Neural Engineering, April 29-May 3, 2009.

[94]    Amin Katouzian, Elsa D. Angelini, Auranuch Lorsakul, Bernhard Sturm, and Andrew F. Laine, “Lumen Border Detection of Intravascular Ultrasound via Denoising of Directional Wavelet Representations,” Proceedings of the Functional Imaging and Modeling of the Heart (FIMH 2009), pp. 104-113, Nice, France, June 3-5, 2009.

[95]    J. Caban, N. Lee, S. Ebadollahi, A. F. Laine, " Concept Detection in Longitudinal Brain MR Images Using Multi-Modal Cues", Proceeding of 6th IEEE International Symposium on Biomedical Imaging (ISBI): From Nano to Macro,June 28-July 1, 2009, Boston Massachusetts, USA, pp. 418-421.

[96]    Q. Duan, K. M. Parker, A. Lorsakul, E. D. Angelini, E. Hyodo, S. Homma, J. W. Holmes, and A. F. Laine , " Quantitative Validation of Optical Flow Based Myocardial Strain Measures Using Sonomicrometry", Proceedings of the 2009 IEEE International Symposium on Biomedical Imaging: From Nano to Macro (ISBI), June 28-July 1, 2009, Boston Massachusetts, USA, pp. 454-457.

[97]    N. Lee, A.F. Laine, R.T. Smith, "Bayesian Transductive Markov Random Fields for Interactive Segmentation in Retinal Disorders", Proceedings of the 11th International Congress of Medical Physics and Biomedical Engineering, vol. 25/11, pp. 227-230, Munich, Germany, 2009.

[98]    N. Lee, J. Caban, S. Ebadollahi, A. F. Laine, " Interactive Segmentation in Multi-Modal Medical Imagery using a Bayesian Transductive Learning Approach", Proceedings of SPIE Medical Imaging, vol. 7260 (2009), pp. 72601W-72601W-10, Florida, USA, 2009.

[99]    N. Lee, J. Wielaard, A. A. Fawzi, P. Sajda, A. F. Laine, G. Martin, M. S. Humayun, R. T. Smith, " In vivo snapshot hyperspectral image anlaysis of age-related macular degeneration,” Proc. IEEE Eng. Med. Biol. Soc.(EMBC2010), Aug 31-Sep 4, Buenos Aires, Argentina, 2010.

[100]    M. J. Po, A. Lorsakul, Q. Duan, K. J. Yeroushalmi, E. Hyodo, Y. Oe, S. Homma, and A. F. Laine, “In-Vivo Clinical Validation of Cardiac Deformation and Strain Measurements from 4D Ultrasound,” Proc. IEEE Eng. Med. Biol. Soc. (EMBC2010), Aug 31-Sep 4, Buenos Aires, Argentina, 2010.

[101]    W. H. Lee, Z. Deng, T. Kim, A. F. Laine, S. H. Lisanby, and A. V. Peterchev, “Regional Electric Field Induced by Electroconvulsive Therapy: A FiniteElement Simulation Study,” Proc. IEEE Eng. Med. Biol. Soc.(EMBC2010), Aug 31-Sep 4, Buenos Aires, Argentina, 2010.

[102]    A. Katouzian, E. D. Angelini, B. Sturm, and A. F. Laine, “Automatic Detection of Luminal Borders in IVUS Images by Magnitude-Phase Histograms of Complex Brushlet Coefficients”, Proc. IEEE Eng. Med. Biol. Soc.(EMBC2010), Aug 31-Sep 4, Buenos Aires, Argentina, 2010.

[103]    A. Klein, Noah Lee, Andrew F Laine "Towards a Deep Learning Approach to Brain Parcellation", Proceedings of the IEEE International Symposium on Biomedical Imaging: From Nano to Macro (ISBI), Mar. 30th-Apr. 2nd, Chicago Illinois, USA, 2011

[104]    Auranuch Lorsakul, Qi Duan, Ming Jack Po, Shunichi Homma, Elsa Angelini, Andrew F Laine "Parameterization of Real-Time 3D Speckle Tracking Framework for Cardiac Strain Assessment", Proceedings of the IEEE International Conference of Engineering in Medicine and Biology Society (EMBC): Integrating Technology and Medicine for a Healthier Tomorrow, Aug. 30th-Sept. 3rd, Boston Massachusetts, USA, 2011.

[105]    Ming Jack Po, Auranuch Lorsakul, Andrew F Laine "A Momentum-Based Constraint on Optical Flow Tracking of the Endocardial Surface", Proceedings of the IEEE International Conference of Engineering in Medicine and Biology Society (EMBC), 2011.

[106]     Won Hee Lee, Z. D. Deng, Andrew F Laine, S. H. Lisanby, and A. V. Peterchev, "Influence of White Matter Conductivity Anisotropy on Electric Field Strength Induced by Electroconvulsive Therapy", Proceedings of the IEEE International Conference of Engineering in Medicine and Biology Society (EMBC), pp 5473 - 5476., 2011.

[107]     J. Hu, F. Wang, J. Sun, S. Ebadollahi, Noah Lee, Andrew F Laine "Mining Electronic Medical Records to Explore the Linkage Between Healthcare Resource Utilization and Disease Severity in Diabetic Patients ", IEEE Conference on Healthcare Informatics, Imaging, and Systems Biology (HISB), San Jose, California, 2011.

[108]     M. Srichai, Ming Jack Po, Andrew F Laine "Quantitative Detection of Left Ventricular Dyssynchrony From Cardiac Computed Tomography Angiography", Proceedings of the IEEE International Symposium on Biomedical Imaging: From Nano to Macro (ISBI), Mar. 30th-Apr. 2nd, Chicago Illinois, USA, 2011.

[109]    Won Hee Lee, S. H. Lisanby, Andrew F Laine, A. V. Peterchev, "Stimulation strength and focality of electroconvulsive therapy with individualized current amplitude: a preclinical study", Proceedings of the IEEE Engineering in Medicine and Biology Society (EMBC), Aug. 28th-Sept. 1st, San Diego, USA, 2012.

[110]     Arthur, Francesca Zanderigo, Mika Naganawa, Andrew F Laine, "Brain Tissue Selection Procedures for Image Derived Input Functions Derived using Independent Components Analysis", Proceedings of the IEEE Engineering in Medicine and Biology Society (EMBC), Aug. 28th-Sept. 1st, San Diego, USA, 2012, 2012.

[111]     Won Hee Lee, S. H. Lisanby, Andrew F Laine, A. V. Peterchev, "Finite element model of the rhesus macaque head: electroconvulsive therapy electric field simulation", Human Brain Mapping, Beijing, China, 2012.

[112]     Yrjö Häme, Viktor Gamarnik, Katherine M. Parker, Jeffrey W. Holmes, Andrew F Laine, "Level set-based tracking of the endocardium without a shape prior from 3D ultrasound images", International Symposium on Biomedical Imaging, 2012.

[113]     Won Hee Lee, S. H. Lisanby, R. M. Curtis, A. V. Peterchev, Andrew F Laine, "Stimulation strength in hippocampus for various ECT electrode configurations computed in a realistic head model", International Society for ECT and Neuromodulation (ISEN), Philadelphia, Pennsylvania, USA, 2012.

[114]     Shunichi Homma, Andrew F Laine, Elsa Angelini, C. Russo, Qi Duan, Auranuch Lorsakul "Impact of Temporal Resolution on LV Myocardial Regional Strain Assessment with Real-Time 3D Ultrasound", Proceedings of the IEEE Engineering in Medicine and Biology Society (EMBC), Aug 28 - Sept 1, San Diego, USA, 2012.

[115]     Bernhard Sturm, Amin Katouzian, Elsa Angelini, Andrew F Laine "Brushlet Segmentation for Automatic Detection of Lumen Borders in IVUS Images; A Comparison Study", IEEE International Symposium on Biomedical Engineering (ISBI), 2012.

[116]     Athanasios Karamalis, Nassir Navab, Amin Katouzian, Andrew F Laine "A Systematic Approach Toward Reliable Atherosclerotic Plaque Characterization in IVUS Images", Accepted in Bildverarbeitung für die Medizin 2012, Berlin, Germany, 2012.

[117]     Won Hee Lee, Sarah H. Lisanby, Anderw F. Laine, Angel V. Peterchev, "Anatomical variability predicts individual differences in transcranial electric stimulation motor threshold", Proceedings of the IEEE International Conference of Engineering in Medicine and Biology Society (EMBC), Osaka, Japan , 2013.

[118]     Won Hee Lee, Sarah H. Lisanby, Andrew F. Laine, Angel V. Peterchev, "Electric field characteristics of electroconvulsive therapy with individualized current amplitude: a preclinical study", Proceedings of the IEEE International Conference of Engineering in Medicine and Biology Society (EMBC), Osaka, Japan , 2013.

[119]     Won Hee Lee, Sarah H. Lisanby, Andrew F. Laine, Angel V. Peterchev, "Individual variability predicts individual differences in ECT seizure threshold: a combined preclinical and computational modeling study", International Society for ECT and Neuromodulation (ISEN), San Francisco, CA, USA , 2013.

[120]     Arthur Mikhno, Elsa Angelini, Andrew F Laine, "Locally weighted Total Variation denoising for ringing artifact suppression in PET reconstruction using PSF modeling", IEEE International Symposium on Biomedical Imaging (ISBI), San Francisco, CA, USA, 2013.

[121]     Yrjö Häme, Elsa Angelini, Andrew F Laine "Robust quantification of pulmonary emphysema with a hidden Markov measure field model", IEEE International Symposium on Biomedical Imaging (ISBI), San Francisco, CA, USA, 2013.

[122]    A. Mikhno, E. Angelini, A. Laine, "Locally weighted total variation denoising for     PSF modeling artifact suppression in PET reconstruction", IEEE International     Symposium on Biomedical Imaging (ISBI), Beijing, China, May, 2014.

 


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